Linden, Rafael


Universidad o Centro de Investigación: Universidade Federal do Rio de Janeiro  

Departamento, unidad o laboratorio: Instituto de Biofisica Carlos Chagas Filho  

Dirección postal: CCS- Bloco G - Cidade Universitária  

Código postal: 21.941-590  

País: Brasil  

Teléfonos de contacto:  

-9081  

Fax: 55-21-2280-8193  

Correos electrónicos de contacto:  

 rlinden@biof.ufrj.br 


Linea(s) de investigación

Mechanisms of control of programmed cell death and of intercellular neurotrophic signaling, using various experimental models, including glioblastoma and other tumor cell lines.

Miembros del grupo

Publicaciones más relevantes


Interleukin-4 blocks thapsigargin-induced cell death in rat rod photoreceptors: Involvement of cAMP/PKA pathway.
Adão-Novaes J, Guterres CD, da Silva AG, Campello-Costa P, Linden R, Sholl-Franco A.
J Neurosci Res. 2009, 87:2167-74


Evaluation of the pharmacotherapeutic efficacy of Garcinia cambogia plus Amorphophallus konjac for the treatment of obesity.
Vasques CA, Rossetto S, Halmenschlager G, Linden R, Heckler E, Fernandez MS, Alonso JL.
Phytother Res. 2008, 22:1135-40.


Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol.
da Fonseca CO, Linden R, Futuro D, Gattass CR, Quirico-Santos T.
Arch Immunol Ther Exp (Warsz). 2008, 56:267-76.


Comparison of immunological status of African and European cord blood mononuclear cells.
Köhler C, Adegnika AA, Van der Linden R, Agnandji ST, Chai SK, Luty AJ, Szepfalusi Z, Kremsner PG, Yazdanbakhsh M.
Pediatr Res. 2008, 64:631-6.


Nuclear proteasomal degradation and cytoplasmic retention underlie early nuclear exclusion of transcription factor Max upon axon damage.
Petrs-Silva H, Chiarini LB, Linden R.
Exp Neurol. 2008, 213:202-9.


Endocytosis of prion protein is required for ERK1/2 signaling induced by stress-inducible protein 1.
Caetano FA, Lopes MH, Hajj GN, Machado CF, Pinto Arantes C, Magalhães AC, Vieira Mde P, Américo TA, Massensini AR, Priola SA, Vorberg I, Gomez MV, Linden R, Prado VF, Martins VR, Prado MA.
J Neurosci. 2008, 28:6691-702.


Physiology of the prion protein.
Linden R, Martins VR, Prado MA, Cammarota M, Izquierdo I, Brentani RR.
Physiol Rev. 2008, 88:673-728.


Interleukin-4 blocks proliferation of retinal progenitor cells and increases rod photoreceptor differentiation through distinct signaling pathways.
da Silva AG, Campello-Costa P, Linden R, Sholl-Franco A.
J Neuroimmunol. 2008, 196:82-93.


A role for CK2 upon interkinetic nuclear migration in the cell cycle of retinal progenitor cells.
Carneiro AC, Fragel-Madeira L, Silva-Neto MA, Linden R.
Dev Neurobiol. 2008, 68:620-31.


DNA damage-induced cell death: lessons from the central nervous system.
Borges HL, Linden R, Wang JY.
Cell Res. 2008, 18:17-26.


Does the use of recombinant AAV2 in pulmonary gene therapy damage lung function?
Lassance RM, Pássaro CP, Martini SV, Castiglione RC, Gutierrez TM, Abreu SC, Antunes MA, Xisto DG, Cebotaru L, Petrs-Silva H, Zin WA, Guggino WB, Linden R, Rocco PR, Morales MM.
Respir Physiol Neurobiol. 2008, 160:91-8.


Development of a ligand blot assay using biotinylated live cells.
De Almeida Dias F, Souza Dos Santos AL, Ferreira-Pereira A, Romeiro A, Teixeira Zimmermann L, Cunha do Nascimento MT, Correa Atella G, Saraiva EM, Linden R, Hampshire Lopes A.
J Biomol Screen. 2007, 12:1006-10.


Contrast enhanced ultrasound flash replenishment method for directed prostate biopsies.
Linden RA, Trabulsi EJ, Forsberg F, Gittens PR, Gomella LG, Halpern EJ.
J Urol. 2007, 178:2354-8


STI1 promotes glioma proliferation through MAPK and PI3K pathways.
Erlich RB, Kahn SA, Lima FR, Muras AG, Martins RA, Linden R, Chiarini LB, Martins VR, Moura Neto V.
Glia. 2007, 55:1690-8.


Hop/STI1 modulates retinal proliferation and cell death independent of PrPC.
Arruda-Carvalho M, Njaine B, Silveira MS, Linden R, Chiarini LB.
Biochem Biophys Res Commun. 2007, 361:474-80.


Signaling induced by hop/STI-1 depends on endocytosis.
Americo TA, Chiarini LB, Linden R.
Biochem Biophys Res Commun. 2007, 358:620-5.


Epidermal growth factor released in human dental pulp following orthodontic force.
Derringer K, Linden R.
Eur J Orthod. 2007, 29:67-71.


Antifungal Pisum sativum defensin 1 interacts with Neurospora crassa cyclin F related to the cell cycle.
Lobo DS, Pereira IB, Fragel-Madeira L, Medeiros LN, Cabral LM, Faria J, Bellio M, Campos RC, Linden R, Kurtenbach E.
Biochemistry. 2007, 46:987-96.

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